Pharmacodynamic study
Service items
Pharmacodynamic studies can be used to predict the effectiveness of drugs in animals. The established models include:
■ Respiratory diseases: pulmonary fibrosis model, pulmonary embolism
■ Digestive system diseases: various gastric ulcer and duodenal ulcer, reflux esophagitis, functional constipation model, diarrhea model
■ Circulation and blood system diseases: acute and chronic heart failure, myocardial ischemia, myocardial ischemia reperfusion, myocardial infarction
■ Metabolic system diseases: diabetes model, obesity model, hypopituitarism model, clamp test
Neuropsychiatric diseases: cerebral ischemia model, cerebral ischemia reperfusion model
■ Immune related diseases: arthritis model
■ Tumor: subcutaneous and orthotopic tumor
■ Respiratory diseases: pulmonary fibrosis model, pulmonary embolism
■ Digestive system diseases: various gastric ulcer and duodenal ulcer, reflux esophagitis, functional constipation model, diarrhea model
■ Circulation and blood system diseases: acute and chronic heart failure, myocardial ischemia, myocardial ischemia reperfusion, myocardial infarction
■ Metabolic system diseases: diabetes model, obesity model, hypopituitarism model, clamp test
Neuropsychiatric diseases: cerebral ischemia model, cerebral ischemia reperfusion model
■ Immune related diseases: arthritis model
■ Tumor: subcutaneous and orthotopic tumor
Service advantages
＞Carotid sinus blood collection technique:
Animals do not require anesthesia, have minimal trauma, comply with animal ethics, and can meet the blood collection requirements for PK/TK.
＞Bile duct intubation technique in conscious rats:
The use of bile duct catheterization and extracorporeal catheterization can achieve continuous bile collection in conscious rats for more than 72 hours.
＞Cerebrospinal fluid collection technology:
Can collect cerebrospinal fluid from conscious/anesthetized animals for blood-brain barrier permeability research.
Animals do not require anesthesia, have minimal trauma, comply with animal ethics, and can meet the blood collection requirements for PK/TK.
＞Bile duct intubation technique in conscious rats:
The use of bile duct catheterization and extracorporeal catheterization can achieve continuous bile collection in conscious rats for more than 72 hours.
＞Cerebrospinal fluid collection technology:
Can collect cerebrospinal fluid from conscious/anesthetized animals for blood-brain barrier permeability research.
